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The Transformative Power of Next-Generation Sequencing (NGS): Applications in Clinical Diagnostics, Cancer Research, and
Next-Generation Sequencing (NGS) represents a paradigm shift from traditional methods, allowing for the rapid, cost-effective, and simultaneous sequencing of millions of DNA fragments in a high-throughput manner. This powerful technology provides unprecedented insights into the entire human genome, transcriptomes, and epigenomes, fueling discoveries in human biology and disease etiology across multiple disciplines.
NGS has revolutionized molecular diagnostics, enabling the precise identification of disease-causing mutations in conditions like rare pediatric syndromes and complex cancers by detecting a broader spectrum of genetic variation. Its capability to analyze whole genomes and exomes without prior bias makes it an indispensable tool for personalized medicine and large-scale population health studies.
